Ad-blindness is a condition where a site visitor, whether consciously or subconsciously, ignores ads placed on a site. It can be caused by several factors, such as familiar and predictable ad placement spots.
You can apply a few techniques to reduce this effect to help you get more clicks from your Google AdSense program, though this can be applied to any other advertisement or Pay per Click (PPC) program you're running on your site.
Website visitors normally focus on the site's content (while trying not to look at the ads), so blending your AdSense ad units with the layout and color of your site normally produces more clicks. It's not to trick your visitors into thinking that the ads are your site's content, but so that it gets read.
Your site's elements such as images, widgets, or videos normally attract your visitor's attention. Placing your ad unit close to them would get some of the attention. Be careful not to violate Google AdSense's term of service, though.
When a visitor is used to your website's layout and your AdSense units placement, they'll go straight to your site's content and skipping the ads whenever they visit your website. Having a fresh layout or maybe just a different placement for your ads once in a while would be good.
Just as having a new site and ad placement layout, changing the color of your ad units would give the same effect.
Having too many AdSense ad units on a page would make your website visitor more careful of ads. Try reducing the number, and your site would feel more ad-neutral, and visitors would have more focus on your remaining ad units.
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