import pandas as pd

orders = pd.DataFrame(
    {
        "order_id": [1041, 1042, 1043, 1044, 1045, 1046],
        "region": ["EMEA", "APAC", "AMER", "EMEA", "APAC", "AMER"],
        "quantity": [4, 12, 8, 15, 18, 11],
        "status": ["open", "open", "open", "paid", "open", "open"],
    }
)

eligible_regions = ["EMEA", "APAC"]

priority_mask = (
    orders["region"].isin(eligible_regions)
    & (orders["quantity"] >= 10)
    & (orders["status"] == "open")
)

priority_orders = orders.loc[
    priority_mask,
    ["order_id", "region", "quantity", "status"],
]

assert priority_orders.index.tolist() == [1, 4]
assert priority_orders["region"].isin(eligible_regions).all()
assert priority_orders["quantity"].ge(10).all()
assert priority_orders["status"].eq("open").all()

print(priority_orders.to_string())